Afizagabar
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Afizagabar

SKU T37388-25 mg Category Brand:

Price range: 3,040 CAD through 5,440 CAD

Products Details

Product Description

– Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. It enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy [1].

Web ID

– T37388

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H12FN3O2S

References

– Etherington LA, et al. Selective inhibition of extra-synaptic α5-GABAA receptors by S44819, a new therapeutic agent. Neuropharmacology. 2017;125:353-364.

CAS Number

– 1398496-82-6

Molecular Weight

– C19H12FN3O2S

SMILES

– CC1=NN=C(c2cc3c(F)cccc3s2)c2cc3oc(=O)[nH]c3cc2C1

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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