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AEOL-10150 (pentachloride)
$270 – $1,850
Products Details
Product Description
– AEOL-10150 pentachloride is a metalloporphyrin catalytic antioxidant and is a superoxide dismutase mimetic, and protects lungs from radiation-induced injury[1].
Web ID
– HY-19416
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C48H56Cl5MnN12
References
– [1]Rabbani ZN, et al. Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury. Int J Radiat Oncol Biol Phys. 2007 Feb 1;67(2):573-80.|[2]Zhang XR, Zhou WX, Zhang YX. Improvements in SOD mimic AEOL-10150, a potent broad-spectrum antioxidant. Mil Med Res. 2018;5(1):30.
CAS Number
– 286475-30-7
Molecular Weight
– 1033.24
Compound Purity
– 98.0
SMILES
– CC[N+](C=CN1CC)=C1C2=C(C=CC3=C(C(N4CC)=[N+](C=C4)CC)C5=[N]6C(C=C5)=C7C(N8CC)=[N+](C=C8)CC)[N-]3[Mn+3]96[N]%10=C2C=CC%10=C(C(N%11CC)=[N+](C=C%11)CC)C%12=CC=C7[N-]9%12.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
