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ADTL-SA1215
SKU
HY-139742-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Epigenetics, Sirtuin
$240 – $1,950
Products Details
Product Description
– ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative breast cancer.
Web ID
– HY-139742
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H29I2NO3
References
– [1]Zhang J, et al. Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14192-14216.
CAS Number
– 782387-91-1
Molecular Weight
– 657.32
Compound Purity
– 99.23
SMILES
– O=C(C1=C(CCCC)OC2=CC=CC=C12)C3=CC(I)=C(OCCCN4CCCC4)C(I)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Sirtuin
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.