ADH-503

SKU T7776-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 461 CAD

Products Details

Product Description

– ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist that can lead to repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhancement of dendritic cell responses.

Web ID

– T7776

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H28N2O5S2

References

– Panni RZ, et al. Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies. Sci Transl Med. 2019 Jul 3;11(499).

CAS Number

– 2055362-74-6

Molecular Weight

– C27H28N2O5S2

Compound Purity

– 0.9828

SMILES

– C[N+](C)(C)CCO.[O-]C(=O)c1ccc(cc1)-c1ccc(C=C2/SC(=S)N(Cc3ccccc3)C2=O)o1

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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