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Products Details
Product Description
– ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist that can lead to repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhancement of dendritic cell responses.
Web ID
– T7776
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H28N2O5S2
References
– Panni RZ, et al. Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies. Sci Transl Med. 2019 Jul 3;11(499).
CAS Number
– 2055362-74-6
Molecular Weight
– C27H28N2O5S2
Compound Purity
– 0.9828
SMILES
– C[N+](C)(C)CCO.[O-]C(=O)c1ccc(cc1)-c1ccc(C=C2/SC(=S)N(Cc3ccccc3)C2=O)o1
Pathway
– Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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