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ADH-503
$61 – $385
Products Details
Product Description
– ADH-503 ((Z)-Leukadherin-1 choline) is an orally active and allosteric CD11b agonist. ADH-503 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses[1].
Web ID
– HY-15701B
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H28N2O5S2
References
– [1]Panni RZ, et al. Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies. Sci Transl Med. 2019 Jul 3;11(499).
CAS Number
– 2055362-74-6
Molecular Weight
– 524.65
Compound Purity
– 98.04
SMILES
– O=C([O-])C1=CC=C(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)C=C1.OCC[N+](C)(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 21.43 mg/mL (ultrasonic)|Ethanol : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)|Methanol : 100 mg/mL (ultrasonic)
Target
– Complement System
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
