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Adenylyl cyclase type 2 agonist-1
$340 – $1,350
Products Details
Product Description
– Adenylyl cyclase type 2 agonist-1 (Compound 73) is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases[1].
Web ID
– HY-146356
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H17BrClNO5
References
– [1]Guowei Xu, et al. The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation. Eur J Med Chem. 2020 Apr 1;191:112115.
CAS Number
– 2414908-52-2
Molecular Weight
– 550.78
SMILES
– [H][C@@]1(OC2([C@]3(C(N(C([C@@]13[H])=O)C4=CC=CC=C4Cl)=O)[H])C(C5=C(C2=O)C=CC(Br)=C5)=O)C6=CC=C(C=C6)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Adenylate Cyclase
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
