Download Files:
Products Details
Product Description
– Adenosine receptor antagonist 1 is a A2aR-selective antagonist with an IC50 of 0.29 nM and displays 14-fold more selective for A2aR than A2bR.
Web ID
– HY-141865
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H15ClFN7O
References
– [1]Lamb ML, et al. Triazole compounds as adenosine receptor antagonists. WO2021156439A1.
CAS Number
– 2682930-40-9
Molecular Weight
– 447.85
SMILES
– NC1=NC(C2=CC=CC=C2)=C(C3=NC(CC4=C(C=C(C=N4)F)Cl)=NN13)C5=CNC(C=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor
Isoform
– Adenosine A2A receptor (A2AR)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
