Products Details

Product Description

– Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2].

Web ID

– HY-B0228

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C10H13N5O4

References

– [1]Zhou XT, et al. Inhibition of autophagy enhances adenosine induced apoptosis in human hepatoblastoma HepG2 cells. Oncol Rep. 2019;41(2):829-838.|[2]Eltzschig HK. Adenosine: an old drug newly discovered. Anesthesiology. 2009;111(4):904-915.|[3]Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98(3):1591-1625.|[4]Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ. 2007;14(7):1315-1323.

CAS Number

– 58-61-7

Molecular Weight

– 267.24

Compound Purity

– 99.92

SMILES

– NC1=C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C2=NC=N1

Clinical Information

– Launched

Research Area

– Cancer; Metabolic Disease

Solubility

– DMSO : 33.33 mg/mL (ultrasonic)|H2O : ≥ 6.67 mg/mL

Target

– Apoptosis;Autophagy;Endogenous Metabolite;Nucleoside Antimetabolite/Analog

Isoform

– Human Endogenous Metabolite;Microbial Metabolite

Pathway

– Apoptosis;Autophagy;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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