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Adenanthin
Products Details
Product Description
– Adenanthin is an inhibitor of thiol-dependent antioxidant enzymes, targeting to Prx 1 and Prx 2. Adenanthin impairs human natural killer (NK) cells effector functions, and killing hepatocellular carcinoma cells. Adenanthin inhibits NF-κB signaling and lipogenesis and the development of obesity by regulating ROS[1].
Web ID
– HY-N2819
Shipping
– Room temperature
Molecular Formula
– C26H34O9
References
– [1]Hu J, et al. Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS. Molecules. 2019 Jan 3;24(1):158.
CAS Number
– 111917-59-0
Molecular Weight
– 490.54
SMILES
– CC(O[C@@H]1[C@]23[C@]([C@H](C[C@](C(C3=O)=C)([H])C2)OC(C)=O)([H])[C@]4([C@](C(C)([C@H](C[C@@H]4OC(C)=O)O)C)([H])C1=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB
Pathway
– NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.