Adavivint
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Adavivint

SKU T5636-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 878 CAD

Products Details

Product Description

– Adavivint (SM04690) is a selective inhibitor of the typical Wnt signaling pathway. In SW480 cells, EC50=19.5 nM was measured using high-throughput TCF/LEF reporter gene experiments.

Web ID

– T5636

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H24FN7O

Citations

– 1. Wang C, Wang T, He Q, et al.Inhibition of the canonical Wnt/β-catenin pathway interferes with macropinocytosis to suppress pseudorabies virus proliferation.Veterinary Microbiology.2025: 110373.

References

– Yazici Y , Mcalindon T E , Fleischmann R , et al. A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study[J]. Osteoarthritis & Cartilage, 2017, 25(10):1598.

CAS Number

– 1467093-03-3

Molecular Weight

– C29H24FN7O

Compound Purity

– 0.9827

SMILES

– CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cncc(-c5cccc(F)c5)c4[nH]3)c2c1

Pathway

– Stem Cells|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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