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Products Details
Product Description
– ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC50 value of 73 nM.
Web ID
– HY-132917
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C44H44Br4N6O12S2
References
– [1]Cuffaro D, et al. Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors. ACS Med. Chem. Lett. 2021, 12, 11, 1787–1793.
CAS Number
– 2758892-64-5
Molecular Weight
– 1232.60
SMILES
– O=C(NCCC[C@@H](NS(=O)(C1=CC=C(OCC2=CC(Br)=CC(Br)=C2)C=C1)=O)C(NO)=O)C3=CC=CC(C(NCCC[C@@H](NS(=O)(C4=CC=C(OCC5=CC(Br)=CC(Br)=C5)C=C4)=O)C(NO)=O)=O)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MMP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
