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Products Details
Product Description
– Adafosbuvir (AL-335), a precursor compound of a uridine-based nucleotide analog polymerase (NS5B) inhibitor, has potent antiviral activity against HCV and acts as a potent inhibitor of HCV RNA polymerase[1].
Web ID
– HY-109047
Shipping
– Room temperature
Molecular Formula
– C22H29FN3O10P
References
– [1]Tetsuo Takehara, et al. JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study. J Gastroenterol. 2020 Jun;55(6):640-652.
CAS Number
– 1613589-09-5
Molecular Weight
– 545.45
SMILES
– C[C@@]1([C@H](N(C=CC2=O)C(N2)=O)O[C@@](COP(OC3=CC=CC=C3)(N[C@@H](C)C(OC(C)C)=O)=O)(F)[C@H]1O)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis;HCV
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
