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Aconine
$140 – $230
Products Details
Product Description
– Aconine inhibits receptor activator of nuclear factor (NF)-κB ligand (RANKL)-induced NF-κB activation.
Web ID
– HY-N0277
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H41NO9
References
– [1]Zeng XZ, et al. Aconine inhibits RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing NF-κB and NFATc1 activation and DC-STAMP expression. Acta Pharmacol Sin. 2016 Feb;37(2):255-63.
CAS Number
– 509-20-6
Molecular Weight
– 499.59
Compound Purity
– 99.78
SMILES
– O[C@@H]1C[C@H](OC)[C@@]23[C@]([H])(C4)[C@]5([H])[C@@H](O)[C@@]4(O)[C@@H](OC)[C@H](O)[C@]5(O)[C@H]6[C@H](OC)[C@@]([H])2[C@]1(COC)CN(CC)[C@H]63
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– NF-κB
Isoform
– NF-κB
Pathway
– NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
