Products Details

Product Description

– AChE/BuChE-IN-4(compound 4a) is aorally activeandbrain-penetrantmultitarget-directedAChE/BuChEinhibitor againstAChEandBuChE, with theIC50of 2.08 and 7.41 μM[1].

Web ID

– HY-155349

Shipping

– Room temperature

Molecular Formula

– C17H23N5

References

– [1]Conceição RAD, et al. Structure-based design of new N-benzyl-piperidine derivatives as multitarget-directed AChE/BuChE inhibitors for Alzheimer’s disease [published online ahead of print, 2023 Oct 5]. J Cell Biochem. 2023;10.1002/jcb.30483.

CAS Number

– 1997158-25-4

Molecular Weight

– 297.40

SMILES

– NC1=NC=CC(NCC2CCN(CC2)CC3=CC=CC=C3)=N1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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