Products Details

Product Description

– AChE/BChE-IN-2 (Compound 13b) is a potent inhibitor of AChE/BChE (AChE IC50 = 0.96 ± 0.14 µM, BChE IC50 = 1.23 ± 0.23 µM). AChE/BChE-IN-2 has the potential for the research of AD diseases[1].

Web ID

– HY-144753

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C23H25N3O5

References

– [1]Singh YP, et al. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer’s disease. Bioorg Med Chem. 2021 Sep 15;46:116385. doi: 10.1016/j.bmc.2021.116385.

CAS Number

– 2761991-42-6

Molecular Weight

– 423.46

SMILES

– O=C(NCC(NCCC1=CNC2=C1C=C(OC)C=C2)=O)/C=C/C3=CC=C(O)C(OC)=C3

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Isoform

– AChE;BChE

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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