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Acetylcysteine
Price range: 53 CAD through 67 CAD
Products Details
Product Description
– Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity.
Web ID
– T0875
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C5H9NO3S
Citations
– 1. Tang Y, Song H, Wang Z, et al.Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations.Cell Reports.2022, 39(2): 110622.
2. Chen T, Leng J, Tan J, et al.Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer.Journal of Medicinal Chemistry.2023
3. Liu X, Jin J, Wu Y, et al.Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy.European Journal of Medicinal Chemistry.2023: 115540.
4. Li Y, Bao Y, Li Y, et al.RSL3 Inhibits Porcine Epidemic Diarrhea Virus Replication by Activating Ferroptosis.Viruses.2023, 15(10): 2080.
5. Liu X, Sun W, Cao J, et al.Acrolein increases the concentration of intracellular Zn2⁺ by producing mitochondrial reactive oxygen species in A549 cells.Toxicology and Industrial Health.2023: 07482337231198350.
6. Zhu M, Tang X, Gong Z, et al. TAD1822-7 induces ROS-mediated apoptosis of HER2 positive breast cancer by decreasing E-cadherin in an EphB4 dependent manner. Life Sciences. 2021: 119954
7. Xu B, Qin Y, Li D, et al. Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway. Redox Biology. 2020, 28: 101342
8. Xu B, Xu J, Cai N, et al. Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. Free Radical Biology and Medicine. 2020
9. Xue J, Liao Q, Luo M, et al. Cigarette smoke-induced oxidative stress activates NRF2 to mediate fibronectin disorganization in vascular formation. Open Biology. 2022, 12(4): 210310
10. Yi Y, Gao K, Lin P, et al. Staphylococcus aureus-Induced Necroptosis Promotes Mitochondrial Damage in Goat Endometrial Epithelial Cells. Animals. 2022, 12(17): 2218.
References
– Supabphol A, et al. N-acetylcysteine inhibits proliferation, adhesion, migration and invasion of human bladder cancer cells. J Med Assoc Thai. 2009 Sep;92(9):1171-7.
CAS Number
– 616-91-1
Molecular Weight
– C5H9NO3S
Compound Purity
– 0.9995
SMILES
– [C@@H](NC(C)=O)(C(O)=O)CS
Target
– Others
Pathway
– Metabolism|||Apoptosis|||Microbiology/Virology|||Immunology/Inflammation|||NF-κB
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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