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Ac-LEHD-AMC
Products Details
Product Description
– Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].
Web ID
– HY-D1652
Shipping
– Room temperature
Molecular Formula
– C33H41N7O11
References
– [1]Igor M Prudnikov, et al. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: an approach for the differential identification of proteases. J Biochem. 2012 Mar;151(3):299-316.
CAS Number
– 292633-16-0
Molecular Weight
– 711.72
SMILES
– CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC2=CN=CN2)=O)=O)C=C1O3)=CC3=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Caspase
Pathway
– Apoptosis
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.