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Products Details
Product Description
– Ac-Ile-Glu-Thr-Asp-pNA is a caspase-8 substrate that undergoes enzymatic binding and cleavage specifically at the Ile-Glu-Thr-Asp (IETD) peptide sequence, resulting in the release of p-nitroalinide, which can be quantitatively measured using colorimetric detection at 405 nm as an indicator of caspase-8 enzyme activity.
Web ID
– T39672
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H38N6O12
References
– Smith GK, et al. Expression, preparation, and high-throughput screening of caspase-8: discovery of redox-based and steroid diacid inhibition. Arch Biochem Biophys. 2002;399(2):195-205.
CAS Number
– 219138-21-3
Molecular Weight
– C27H38N6O12
SMILES
– CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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