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Abrocitinib
Price range: 123 CAD through 1,968 CAD
Products Details
Product Description
– Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).
Web ID
– TQ0037
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H21N5O2S
References
– Vazquez ML, et al. Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. J Med Chem. 2018 Feb 8;61(3):1130-1152.
CAS Number
– 1622902-68-4
Molecular Weight
– C14H21N5O2S
Compound Purity
– 0.9991
SMILES
– CCCS(=O)(=O)N[C@H]1C[C@H](C1)N(C)c1ncnc2[nH]ccc12
Pathway
– Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Stem Cells
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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