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ABP688
$50 – $610
Products Details
Product Description
– ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1].
Web ID
– HY-110141
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H16N2O
References
– [1]Hintermann S, et al. ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies. Bioorg Med Chem. 2007 Jan 15;15(2):903-14.
CAS Number
– 924298-51-1
Molecular Weight
– 240.30
Compound Purity
– 98.02
SMILES
– CC1=NC(C#CC2=C/C(CCC2)=N/OC)=CC=C1
Clinical Information
– Phase 1
Research Area
– Others
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– mGluR
Isoform
– mGluR5
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
