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AAL-993
61 CAD – 2,288 CADPrice range: 61 CAD through 2,288 CAD
Products Details
Product Description
– AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities.
Web ID
– T21593
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H16F3N3O
References
– Hyun Seung Ban, et al. Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633. Cancer Lett. 2010 Oct 1;296(1):17-26.
CAS Number
– 269390-77-4
Molecular Weight
– C20H16F3N3O
Compound Purity
– 0.9906
SMILES
– FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Target
– ADC Linker
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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