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Products Details
Product Description
– A2A/A3 AR antagonist-1 (compound 23) is a dual A2A/A3 adenosine receptor (AR) fluorescent ligand, with Kis of 90 nM and 31.8 nM for hA2A AR and hA3 AR, respectively[1].
Web ID
– HY-147541
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C56H71N15O12S2
References
– [1]Federico S, et, al. Conjugable A 3 adenosine receptor antagonists for the development of functionalized ligands and their use in fluorescent probes. Eur J Med Chem. 2020 Jan 15;186:111886.
Molecular Weight
– 1210.39
SMILES
– CN1C=C2C(N=C(N3N=C(N=C23)C4=CC=CO4)NC(CCCC5=CN(N=N5)CCCCCCNC(C6=CC(C([O-])=O)=C(C=C6)C7=C8C=CC(C(S(=O)([O-])=O)=C8OC9=C(C(N)=CC=C97)S(=O)([O-])=O)=[NH2+])=O)=O)=N1.CC[NH+](CC)CC.CC[NH+](CC)CC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor
Isoform
– Adenosine A2A receptor (A2AR);Adenosine A3 receptor (A3R)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
