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Products Details
Product Description
– A2A/A1 AR antagonist-1 (compound 1a) is dual potent A2A/A1 AR antagonist with Kis of 5.58 and 24.2 nM, respectively. A2A/A1 AR antagonist-1 has the potential for the research of ischemic stroke[1].
Web ID
– HY-145706
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H12N6O2
References
– [1]Tang ML, et al. Discovery of Pyridone-Substituted Triazolopyrimidine Dual A2A/A1 AR Antagonists for the Treatment of Ischemic Stroke. ACS Med Chem Lett. 2022;13(3):436-442. Published 2022 Feb 21.
CAS Number
– 2445615-24-5
Molecular Weight
– 308.29
SMILES
– O=C1C=CC(C2=CN=C(N3N=C(C4=CC=CO4)N=C23)N)=CN1C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
