A12B4C3

SKU HY-100683-10 mg Category Tags , ,

$700$1,120

Products Details

Product Description

– A12B4C3 is a potent human polynucleotide kinase/phosphatase (hPNKP) inhibitor with an IC50 value of 0.06 μM. A12B4C3 has antiproliferative activity against cancer cells. A12B4C3 can also enhance the radiosensitivity of certain cancer cells[1].

Web ID

– HY-100683

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C30H38N4O5

References

– [1]Freschauf GK, et al. Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase. Cancer Res. 2009 Oct 1;69(19):7739-46.

CAS Number

– 1005129-80-5

Molecular Weight

– 534.65

Compound Purity

– 98.0

SMILES

– O=C1N(C(C2N(C(C(CCCCCCCCCC)O)C=CC12)NC3=CC=C([N+]([O-])=O)C=C3)=O)C4=CC=CC=C4

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 53 mg/mL (ultrasonic;warming)

Target

– Phosphatase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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