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Products Details
Product Description
– A-933548 is a potent and selective inhibitor of calpain, with a Ki of 18 nM. A-933548 can be used for the research of Alzheimer’s disease[1].
Web ID
– HY-113639
Shipping
– Room temperature
Molecular Formula
– C25H21N5O3
References
– [1]Kling A, et, al. Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer’s Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides. J Med Chem. 2017 Aug 24;60(16):7123-7138.
CAS Number
– 1037826-43-9
Molecular Weight
– 439.47
SMILES
– O=C(C1=C(N=CC=C1)N2N=C(C=C2)C3=CC=CC=C3)NC(CC4=CC=CC=C4)C(C(N)=O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Proteasome
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
