A-484954
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A-484954

SKU TQ0137-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 1,304 CAD

Products Details

Product Description

– A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.

Web ID

– TQ0137

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H15N5O3

Citations

– 1. Piserchio A, Isiorho E A, Dalby K N, et al.Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor.Journal of Biological Chemistry.2023: 104813.

References

– Chen Z, et al. 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor. J Biol Chem. 2011 Dec 23;286(51):43951-8.

CAS Number

– 142557-61-7

Molecular Weight

– C13H15N5O3

Compound Purity

– 0.9986

SMILES

– CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O

Pathway

– Microbiology/Virology|||Autophagy|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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