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A-1293102
Products Details
Product Description
– A-1293102 is a potent and selective BCL-XL inhibitor that kills BCL-XL-dependent tumor cells[1].
Web ID
– HY-150266
Shipping
– Room temperature
Molecular Formula
– C42H40F3N7O7S5
References
– [1]Zhi-Fu Tao, et al.Structure-Based Design of A-1293102, a Potent and Selective BCL-XL Inhibitor. ACS Medicinal Chemistry Letters 2021 12 (6), 1011-1016.
CAS Number
– 1565759-96-7
Molecular Weight
– 972.13
SMILES
– O=C(C1=C2C(CCN(C3=NC(C(NS(=O)(C4=CC(S(C(F)(F)F)(=O)=O)=C(C=C4)N[C@@H](CSC5=CC=CC=C5)CCN6CCOCC6)=O)=O)=CS3)C2)=CC=C1)NC7=NC8=CC=CC=C8S7
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
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