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Products Details
Product Description
– A-1211212 (BCL2-IN-1) is a potent Bcl-2 inhibitor. BCL2-IN-1 binds Bcl-2 with a Ki of <0.01 nM[1].
Web ID
– HY-135273
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C47H54ClN7O7S
References
– [1]Nathaniel D. Catron, et al. Solid dispersions containing an apoptosis-inducing agent. WO2012058392A1.
CAS Number
– 1257044-75-9
Molecular Weight
– 896.49
SMILES
– O=C(NS(=O)(C1=CC=C(NC[C@H]2CC[C@H](OC)CC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCN(CC5=C(C6=CC=C(Cl)C=C6)CC(C)(C)CC5)CC4)C=C3OC7=CN=C(NC=C8)C8=C7
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
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