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Products Details
Product Description
– 8A8 is a potent proinflammatory factor NO inhibitor with an IC50 of 4.7 μM. 8A8 also significantly inhibits LPS-induced HaCat cell proliferation[1].
Web ID
– HY-115927
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C36H37BrClN5O9
References
– [1]Zhang F, et al. Design and synthesis of the 4H-chromenone derivatives against psoriasis [published online ahead of print, 2022 Jan 25]. Bioorg Chem. 2022;120:105640.
CAS Number
– 2766594-12-9
Molecular Weight
– 799.06
SMILES
– COC1=CC(OC)=C2C(C(OCC3=CN(N=N3)CCN4CCN(CC4)C(C5=CC(Br)=CC=C5Cl)=O)=C(OC2=C1)C6=CC(OC)=C(C(OC)=C6)OC)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NO Synthase
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
