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8-Demethyl Ivabradine

Products Details

Product Description

– 8-Demethyl Ivabradine is a metabolite of Ivabradine. Ivabradine is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker[1].

Web ID

– HY-131283

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C26H34N2O5

References

– [1]M François-Bouchard,et al. Simultaneous determination of ivabradine and its metabolites in human plasma by liquid chromatography–tandem mass spectrometry. J Chromatogr B Biomed Sci Appl. 2000 Aug 18;745(2):261-9.

CAS Number

– 304464-97-9

Molecular Weight

– 454.56

SMILES

– O=C1N(CCCN(C[C@@H]2C3=CC(OC)=C(OC)C=C3C2)C)CCC4=CC(OC)=C(O)C=C4C1

Clinical Information

– No Development Reported

Research Area

– Endocrinology

Solubility

– 10 mM in DMSO

Target

– Drug Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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