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Product Description
– 8-Deazafolic acid is an antimicrobial drug for the folate-dependent bacteria, Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 74691). 8-Deazafolic acid has activity against lymphoid leukemia L1210 in mice[1].
Web ID
– HY-122518
Shipping
– Room temperature
Molecular Formula
– C20H20N6O6
References
– [1]Carroll Temple Jr, et al. New synthesis of N-[4-[[(2-amino-4(3H)-oxopyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamic acid (8-deazafolic acid) and the preparation of some 5,6,7,8-tetrahydro derivatives. J. Med. Chem. 1981, 24, 10, 1254–1258.
CAS Number
– 51989-25-4
Molecular Weight
– 440.41
SMILES
– O=C(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CC=C(NC(N)=NC3=O)C3=N2)=O)C(O)=O)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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