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Products Details
Product Description
– 7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice[1][2][3].
Web ID
– HY-N12249
Shipping
– Room temperature
Molecular Formula
– C14H15NO6
References
– [1]Wang YH, et al. Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase. J Nat Prod. 2007 Sep;70(9):1458-61.|[2]Zhao D, et al. 7-Deoxy-trans-dihydronarciclasine Isolated from Lycoris chejuensis Inhibits Neuroinflammation in Experimental Models. J Agric Food Chem. 2019 Sep 4;67(35):9796-9804.
CAS Number
– 145987-74-2
Molecular Weight
– 293.27
SMILES
– O=C1C2=CC(OCO3)=C3C=C2[C@]4([H])[C@@]([C@@H]([C@@H]([C@H](C4)O)O)O)([H])N1
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
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