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7-Deaza-2′,3′-dideoxyguanosine
Products Details
Product Description
– 7-Deaza-2′,3′-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM[1].
Web ID
– HY-138592
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C11H14N4O3
References
– [1]Nicholas A Boyle, et al. Synthesis of 2′,3′-dideoxynucleoside 5′-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase. J Med Chem. 2005 Apr 7;48(7):2695-700.
CAS Number
– 111869-49-9
Molecular Weight
– 250.25
SMILES
– O=C1C2=C(N([C@@H]3O[C@H](CO)CC3)C=C2)NC(N)=N1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.