7-Chlorokynurenic acid

SKU T10191L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 1,579 CAD

Products Details

Product Description

– 7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.

Web ID

– T10191L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C10H6ClNO3

References

– Kemp JA, et al. 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc Natl Acad Sci U S A. 1988 Sep;85(17):6547-50.

CAS Number

– 18000-24-3

Molecular Weight

– C10H6ClNO3

Compound Purity

– 0.9972

SMILES

– OC(=O)c1cc(O)c2ccc(Cl)cc2n1

Target

– Others

Pathway

– Neuroscience

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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