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Products Details
Product Description
– 5-HT6 agonist 1 (Compound 19) is a 5-HT6 agonist (Ki: 5 nM). 5-HT6 agonist 1 has antidepressant-like properties, and improves cognitive deficits. 5-HT6 agonist 1 also inhibits platelet aggregation. 5-HT6 agonist 1 has high metabolic stability[1].
Web ID
– HY-155116
Shipping
– Room temperature
Molecular Formula
– C17H22Cl2N6S
References
– [1]Czarnota-Łydka K, et al. Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer’s disease. Eur J Med Chem. 2023 Nov 5;259:115695.
Molecular Weight
– 413.37
SMILES
– CCC(C1=NC(N)=NC(N2CCN(C)CC2)=N1)SC3=C(Cl)C=CC(Cl)=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
