Download Files:
Products Details
Product Description
– 5-HT1A antagonist 1 (compound 6f) is a potent and selective antagonist of 5-HT1A receptor, with a Ki of 35 nM. 5-HT1A antagonist 1 can be used for the research of CNS diseases[1].
Web ID
– HY-144764
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H29ClN6O2
References
– [1]Zaręba P, et, al. New N-aryl-N’-aryl-/(thio)ureido-/sulfamoylamino-derivatives of alkyl/alkylcarbamoyl piperazines: Effect of structural modifications on selectivity over 5-HT 1A receptor. Eur J Med Chem. 2022 May 5;235:114319. Eur J Med Chem. 2022 May 5;235:114319.
Molecular Weight
– 456.97
SMILES
– O=C(N1CCN(CC1)C2=CC(Cl)=CC=C2)NCCCCCCN3N=C4C=CC=CN4C3=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Isoform
– 5-HT1 Receptor;5-HT2 Receptor;5-HT7 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
