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5-Aza-7-deazaguanine
SKU
HY-111627-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
$130 – $1,250
Products Details
Product Description
– 5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides[1].
Web ID
– HY-111627
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C5H5N5O
References
– [1]Fateev IV, et al. Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides. Chemistry. 2015 Sep 14;21(38):13401-19.
CAS Number
– 67410-64-4
Molecular Weight
– 151.13
Compound Purity
– 98.06
SMILES
– O=C1N=C(N)N=C2N1C=CN2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– H2O : 5 mg/mL (ultrasonic;adjust pH to 9 with NaOH)
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.