(4R,5S)-nutlin carboxylic acid

SKU T17873-100 mg Category Brand:

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Products Details

Product Description

– (4R,5S)-Nutlin Carboxylic Acid (MDM2 Ligand 2), a Nutlin 3-based MDM2 ligand, can be conjugated to a protein-binding ligand via a linker to create PROTACs[1].

Web ID

– T17873

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H32Cl2N4O6

References

– Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

CAS Number

– 2306390-08-7

Molecular Weight

– C32H32Cl2N4O6

SMILES

– C(=O)(N1[C@]([C@](N=C1C2=C(OC(C)C)C=C(OC)C=C2)(C3=CC=C(Cl)C=C3)[H])(C4=CC=C(Cl)C=C4)[H])N5CC(=O)N(CC(O)=O)CC5

Target

– Others

Pathway

– Others

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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