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4,9-Anhydrotetrodotoxin
$850
Only 1000 item(s) left in stock.
Products Details
Product Description
– 4,9-Anhydrotetrodotoxin is a selective voltage-gated sodium channel (VGSC) inhibitor that blocks Nav1.1 and Nav1.6 in human brain and induces a hyperpolarizing shift in the voltage dependence of inactivated Nav1.6[1].
Web ID
– HY-126985
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C11H15N3O7
References
– [1]Nicholas Denomme, et al. The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Nav1.1 in addition to Nav1.6. Neurosci Lett. 2020 Apr 17;724:134853.
CAS Number
– 13072-89-4
Molecular Weight
– 301.25
Compound Purity
– 98.0
SMILES
– O[C@@]1(O2)[C@@]3([H])OC(C45)NC(N)=N[C@@]43[C@H](O)[C@@]2([H])[C@@](CO)(O)C5O1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
