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4-IPP
SKU
HY-110063-1 mg
Category Reference compound
Tags Immunology/Inflammation, Macrophage migration inhibitory factor (MIF), Metabolic Disease
$40 – $200
Products Details
Product Description
– 4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF)[1].
Web ID
– HY-110063
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C10H7IN2
References
– [1]Zheng L, et al. Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP suppresses osteoclast formation and promotes osteoblast differentiation through the inhibition of the NF-κB signaling pathway. FASEB J. 2019 Jun;33(6):7667-7683.
CAS Number
– 41270-96-6
Molecular Weight
– 282.08
Compound Purity
– 99.46
SMILES
– IC1=CC(C2=CC=CC=C2)=NC=N1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Macrophage migration inhibitory factor (MIF)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.