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4-IPP

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Products Details

Product Description

– 4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF)[1].

Web ID

– HY-110063

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C10H7IN2

References

– [1]Zheng L, et al. Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP suppresses osteoclast formation and promotes osteoblast differentiation through the inhibition of the NF-κB signaling pathway. FASEB J. 2019 Jun;33(6):7667-7683.

CAS Number

– 41270-96-6

Molecular Weight

– 282.08

Compound Purity

– 99.46

SMILES

– IC1=CC(C2=CC=CC=C2)=NC=N1

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Macrophage migration inhibitory factor (MIF)

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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