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4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
SKU
HY-111513-Get quote
Category Reference compound
Tags Amyloid-β, Neurological Disease, Neuronal Signaling
Products Details
Product Description
– 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent which binds to Amyloid-β (1-40) with a KD of 1.7 nM.
Web ID
– HY-111513
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C14H11BrN2S
References
– [1]Mathis CA, et al. Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. J Med Chem. 2003 Jun 19;46(13):2740-54.|[2]Klunk W, et al. Amyloid imaging as a surrogate marker for efficacy of anti-amyloid therapies.
CAS Number
– 566169-98-0
Molecular Weight
– 319.22
Compound Purity
– 98.60
SMILES
– CNC1=CC=C(C2=NC3=CC=C(Br)C=C3S2)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.