4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine

SKU HY-111513-Get quote Category Tags , ,

Products Details

Product Description

– 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent which binds to Amyloid-β (1-40) with a KD of 1.7 nM.

Web ID

– HY-111513

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C14H11BrN2S

References

– [1]Mathis CA, et al. Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. J Med Chem. 2003 Jun 19;46(13):2740-54.|[2]Klunk W, et al. Amyloid imaging as a surrogate marker for efficacy of anti-amyloid therapies.

CAS Number

– 566169-98-0

Molecular Weight

– 319.22

Compound Purity

– 98.60

SMILES

– CNC1=CC=C(C2=NC3=CC=C(Br)C=C3S2)C=C1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Amyloid-β

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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