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3,5-Diiodothyropropionic acid
$50 – $90
Products Details
Product Description
– 3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].
Web ID
– HY-126236
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H12I2O4
References
– [1]Pennock GD, et al. Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity. J Pharmacol Exp Ther. 1992 Oct;263(1):163-9.
CAS Number
– 1158-10-7
Molecular Weight
– 510.06
Compound Purity
– 99.20
SMILES
– O=C(O)CCC1=CC(I)=C(OC2=CC=C(O)C=C2)C(I)=C1
Clinical Information
– Phase 2
Research Area
– Cardiovascular Disease; Endocrinology
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Thyroid Hormone Receptor
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
