3,5-Diiodothyropropionic acid

$50$90

Products Details

Product Description

– 3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively[1].

Web ID

– HY-126236

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C15H12I2O4

References

– [1]Pennock GD, et al. Cardiac effects of 3,5-diiodothyropropionic acid, a thyroid hormone analog with inotropic selectivity. J Pharmacol Exp Ther. 1992 Oct;263(1):163-9.

CAS Number

– 1158-10-7

Molecular Weight

– 510.06

Compound Purity

– 99.20

SMILES

– O=C(O)CCC1=CC(I)=C(OC2=CC=C(O)C=C2)C(I)=C1

Clinical Information

– Phase 2

Research Area

– Cardiovascular Disease; Endocrinology

Solubility

– DMSO : 50 mg/mL (ultrasonic)

Target

– Thyroid Hormone Receptor

Pathway

– Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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