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(32-Carbonyl)-RMC-5552
$360 – $3,000
Products Details
Product Description
– (32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].
Web ID
– HY-134903
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C93H134N10O24
References
– [1]Jennifer PITZEN, et al. C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors. WO2019212990A1.
CAS Number
– 2382768-55-8
Molecular Weight
– 1776.11
Compound Purity
– 95.04
SMILES
– NC1=C2C(C3=CC=C(OC(N)=N4)C4=C3)=NN(C2=NC=N1)CC5=CC=C(CN(CC6)C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(O[C@H]7[C@@H](C[C@@H](CC7)C[C@H]([C@@]8([H])OC([C@@]9([H])N(CCCC9)C(C([C@@]%10(O[C@](CC[C@H]%10C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C([C@@H]([C@@H](/C(C)=C/[C@H](C(C8)=O)C)O)OC)=O)C)C)OC)O)=O)=O)=O)C)OC)=O)=O)C6=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 146.67 mg/mL (ultrasonic)
Target
– mTOR
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
