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Products Details
Product Description
– 3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].
Web ID
– HY-N1839
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H24O2
References
– [1]Suárez AI, et al. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Nat Prod Commun. 2017 Apr;12(4):533-535.|[2]Jaña F, et al. Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64.
CAS Number
– 178765-54-3
Molecular Weight
– 272.38
SMILES
– OC1=CC=C(/C=C/[C@](C)(C=C)CC/C=C(C)C)C=C1O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Glucosidase
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Natural Products
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