24-Methylenecholesterol

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Products Details

Product Description

– 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology[1][2][3].

Web ID

– HY-133968

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C28H46O

References

– [1]Sun Y, et al. Sterols from Mytilidae show anti-aging and neuroprotective effects via anti-oxidative activity. Int J Mol Sci. 2014 Nov 25;15(12):21660-73.|[2]Chakrabarti P, et al. Changes in Honey Bee Head Proteome in Response to Dietary 24-Methylenecholesterol. Insects. 2020 Oct 29;11(11):743.|[3]Tabas I, et al. The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction. J Clin Invest. 1989 Dec;84(6):1713-21.

CAS Number

– 474-63-5

Molecular Weight

– 398.66

SMILES

– C=C(C(C)C)CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Acyltransferase

Pathway

– Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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