23-epi-26-Deoxyactein

$780$1,250

Products Details

Product Description

– 23-epi-26-Deoxyactein is a natural and orally active anti-obesity and anti-cancer compound[1][2][3].

Web ID

– HY-139058

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C37H56O10

References

– [1]Eun Mi Choi, et al. Deoxyactein Isolated from Cimicifuga racemosa protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity. J Appl Toxicol. 2013 Jun;33(6):488-94.|[2]Jingjing Yuan, et al. Effects of 23-epi-26-deoxyactein on adipogenesis in 3T3-L1 preadipocytes and diet-induced obesity in C57BL/6 mice. Phytomedicine. 2020 Jun 5;76:153264.|[3]Kwang Sik Suh, et al. Deoxyactein protects pancreatic β-cells against methylglyoxal-induced oxidative cell damage by the upregulation of mitochondrial biogenesis. Int J Mol Med. 2017 Aug;40(2):539-548.|[4]Einbond, L.S., et al. Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells. Breast Cancer Res. Treat. 83, 221–231. Breast Cancer Res Treat. 2004 Feb;83(3):221-31.

CAS Number

– 501938-01-8

Molecular Weight

– 660.83

Compound Purity

– 99.45

SMILES

– C[C@]([C@]12C)(C[C@@](O[C@]([C@@](O3)([H])[C@@]43C)(OC4)C5)([H])[C@]2([H])[C@@H]5C)[C@@](CC6)([H])[C@@]7(C[C@H]1OC(C)=O)[C@]([C@]6([H])C8(C)C)(CC[C@@H]8O[C@H](OC[C@H]9O)[C@@H]([C@H]9O)O)C7

Clinical Information

– No Development Reported

Research Area

– Cancer; Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– PPAR

Pathway

– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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