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Products Details
Product Description
– 2-O-Sinapoyl makisterone A (compound 2), a sinapinic acid-ecdysterone hybrid, is a selective inhibitor of COX-2. 2-O-Sinapoyl makisterone A significantly inhibits the expression of COX-2 protein[1].
Web ID
– HY-N11880
Shipping
– Room temperature
Molecular Formula
– C39H56O11
References
– [1]Kakumu Y, et al. Identification of Ecdysteroid Sinapate Esters with COX-2 Inhibitory Effects from Fibraurea recisa Using Molecular Networking and MS2LDA. J Nat Prod. 2023 Aug 25;86(8):1960-1967.
Molecular Weight
– 700.86
SMILES
– COC(C=C1/C=C/C(O[C@H]2C[C@]3(C)[C@]4(CC[C@@]5([C@@](CC[C@]5(C4=CC([C@@]3(C[C@H]2O)[H])=O)O)([H])[C@@](O)([C@H](O)C[C@@H](C)C(C)(C)O)C)C)[H])=O)=C(C(OC)=C1)O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– COX
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
