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2′-MeCCPA
$250 – $400
Products Details
Product Description
– 2′-MeCCPA is a potent and selective A1 adenosine receptors (A1AR) agonist. 2′-MeCCPA efficiently inhibits cAMP modulation in both direct pathway medium spiny neurons (dMSNs) and indirect pathway medium spiny neurons (iMSNs)[1][2].
Web ID
– HY-103180
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H22ClN5O4
References
– [1]J Bhandal, et al. Adenosine a1 receptor activation can protect the myocardium from ischaemia reperfusion injury post reperfusion. BMJ Journals. Volume 104, Issue Suppl 3.|[2]Muntean BS, et al. Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits. Cell Rep. 2018 Jan 2;22(1):255-268.
CAS Number
– 205171-12-6
Molecular Weight
– 383.83
Compound Purity
– 99.79
SMILES
– ClC1=NC2=C(C(NC3CCCC3)=N1)N=CN2[C@H]4[C@@](O)(C)[C@H](O)[C@@H](CO)O4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Adenosine Receptor
Isoform
– Adenosine A1 receptor (A1R)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
