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2-Iminobiotin
$50 – $55
Products Details
Product Description
– 2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].
Web ID
– HY-118700
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H17N3O2S
References
– [1]Zitta K, et al. 2-Iminobiotin Superimposed on Hypothermia Protects Human Neuronal Cells from Hypoxia-Induced Cell Damage: An in Vitro Study. Front Pharmacol. 2018 Jan 11;8:971.|[2]Sup SJ, et al. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem Biophys Res Commun. 1994 Oct 28;204(2):962-8.
CAS Number
– 13395-35-2
Molecular Weight
– 243.33
Compound Purity
– 98.0
SMILES
– [H][C@](CS[C@H]1CCCCC(O)=O)([C@]1([H])N2)NC2=N
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 12.5 mg/mL (ultrasonic)
Target
– NO Synthase
Isoform
– iNOS
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
