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2-Hydroxy atorvastatin (calcium salt)
SKU
HY-128828-1 mg
Category Reference compound
Tags Drug Metabolite, Metabolic Disease, Metabolic Enzyme/Protease
$150 – $290
Products Details
Product Description
– 2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.
Web ID
– HY-128828
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C33H35FN2O6.1/2Ca
References
– [1]Borek-Dohalský V, et al. Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study. Anal Bioanal Chem. 2006 Sep;386(2):275-85.
CAS Number
– 265989-46-6
Molecular Weight
– 594.69
Compound Purity
– 98.67
SMILES
– FC1=CC=C(C2=C(C3=CC=CC=C3)C(C(NC4=CC=CC=C4O)=O)=C(C(C)C)N2CC[C@@H](O)C[C@@H](O)CC(O)=O)C=C1.[Ca].[1/2]
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;adjust pH to 3 with HCl)
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.