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Products Details
Product Description
– 2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10.
Web ID
– HY-103667
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H14O3
References
– [1]Dinkova-Kostova AT, et al. Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway. Cancer Lett. 2007 Jan 8;245(1-2):341-9.
CAS Number
– 131359-24-5
Molecular Weight
– 266.29
Compound Purity
– 99.09
SMILES
– O=C(/C=C/C1=CC=CC=C1O)/C=C/C2=CC=CC=C2O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Caspase
Isoform
– Caspase 10;Caspase 3
Pathway
– Apoptosis
Product type
– Reference compound
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